Platelet-Rich Fibrin Matrix (PRFM)

Mechanism

PRFM is an advanced form of PRP. It uses the patient’s blood, processed to form a fibrin matrix enriched with platelets and growth factors. This matrix provides a scaffold that supports sustained release of growth factors over time, enhancing tissue repair and regeneration.

Effectiveness

More effective than PRP due to the longer-lasting release of growth factors and better structural support for tissue repair.

Advantages

1. Autologous (no rejection risk).

2. Extended healing effects compared to PRP.

3. Acts as a natural scaffold, improving tissue regeneration.

Applications

Similar to PRP: soft tissue injuries, osteoarthritis, surgical wound healing, tendon/ligament injuries, skin rejuvenation.

Disadvantages:

1. Higher cost compared to PRP.

2. Requires specialized equipment and expertise.